Cyp3a4 Enzyme - Pharma

Relevant Publications

3D spheroid HepaRG and fluorescent biphasic tracer for CYP3A4-mediated antibiotic interaction monitoring in sepsis.

Issue Release: 2024

Metabolic transformation of cyclopiazonic acid in liver microsomes from different species based on UPLC-Q/TOF-MS.

Issue Release: 2024

Case report and literature review: management of Paxlovid (nirmatrelvir/ritonavir)-induced acute tacrolimus toxicity in a patient with systemic lupus erythematosus.

Issue Release: 2024

The Role of Intestinal Cytochrome P450s in Vitamin D Metabolism.

Issue Release: 2024

CYP3A4-Mediated Metabolic Activation and Cytotoxicity of Chlortoluron.

Issue Release: 2024

Hepatic OATP1B zonal distribution: Implications for rifampicin-mediated drug-drug interactions explored within a PBPK framework.

Issue Release: 2024

A Study on the Protective Impact of Resveratrol on Liver Damage in Rats with Obstructive Jaundice.

Issue Release: 2024

Development of a Physiologically Based Pharmacokinetic Population Model for Diabetic Patients and its Application to Understand Disease-drug-drug Interactions.

Issue Release: 2024

CYP3A4 inhibitors may influence the quantification of [I]I-FP-CIT SPECT scans.

Issue Release: 2024

Effects of two commonly used antidepressants amitriptyline and fluoxetine on the pharmacokinetics of abrocitinib in rats.

Issue Release: 2024

Adverse event signal mining and serious adverse event influencing factor analysis of fulvestrant based on FAERS database.

Issue Release: 2024

In vitro demonstration of antedrug mechanism of a pharmacokinetic booster to improve CYP3A4 substrates by CYP3A4-mediated metabolism inhibition.

Issue Release: 2024

PBPK modeling: What is the role of CYP3A4 expression in the gastrointestinal tract to accurately predict first-pass metabolism?

Issue Release: 2024

Embryonic exposure to flubendiamide induces hepatotoxicity in domestic chicks by altering drug-metabolizing enzymes, antioxidant status, and liver function.

Issue Release: 2024

Cadmium causes spleen toxicity in chickens by regulating mitochondrial unfolded protein response and nuclear receptors response.

Issue Release: 2024

The Impact of Baohuoside I on the Metabolism of Tofacitinib in Rats.

Issue Release: 2024

The acute toxic effect of Chinese medicine Fuzi is exacerbated in kidney yang deficiency mice due to metabolic difference.

Issue Release: 2024

Effectiveness and Safety of Different Oral Anticoagulants with P-glycoprotein/ CYP3A4 Inhibitors: A Network Meta-analysis.

Issue Release: 2024

Effects of Clarithromycin and Ketoconazole on FK506 Metabolism in Different CYP3A4 Genotype Recombinant Metabolic Enzyme Systems.

Issue Release: 2024

Effect of Age, Comedications, and CYP3A4/5 Polymorphisms on Perampanel Exposure in Chinese Pediatric Patients With Epilepsy.

Issue Release: 2024

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