Small Interfering Rna (sirna) - Pharma

Relevant Publications

Optimized RNA interference therapeutics combined with interleukin-2 mRNA for treating hepatitis B virus infection.

Issue Release: 2024

Flexible nano-liposomes-encapsulated recombinant UL8-siRNA (r/si-UL8) based on bioengineering strategy inhibits herpes simplex virus-1 infection.

Issue Release: 2024

Expression of Forkhead Box M1 (FOXM1) and anticancer effects of FOXM1 inhibition in epithelial sarcoma.

Issue Release: 2024

Asymmetric bulges within hairpin RNA transgenes influence small RNA size, secondary siRNA production and viral defence.

Issue Release: 2024

A novel multitargeted self-assembling peptide-siRNA complex for simultaneous inhibition of SARS-CoV-2-host cell interaction and replication.

Issue Release: 2024

Dual Effect by Chemical Electron Transfer Enhanced siRNA Lipid Nanoparticles: Reactive Oxygen Species-Triggered Tumor Cell Killing Aggravated by Nrf2 Gene Silencing.

Issue Release: 2024

Advancements and Future Prospects in Molecular Targeted and siRNA Therapies for Chronic Myeloid Leukemia.

Issue Release: 2024

Protocol for siRNA-mediated U1 snRNA knockdown using fluorinated α-helical polypeptide in vitro and in vivo.

Issue Release: 2024

Role of Microglial Mitophagy in Alleviating Postoperative Cognitive Dysfunction: a Mechanistic Study.

Issue Release: 2024

siRNA therapy in osteoarthritis: targeting cellular pathways for advanced treatment approaches.

Issue Release: 2024

Neutralization of CX3CL1 Attenuates TGF-β-Induced Fibroblast Differentiation Through NF-κB Activation and Mitochondrial Dysfunction in Airway Fibrosis.

Issue Release: 2024

Echinatin suppresses cutaneous squamous cell carcinoma by targeting GSTM3-mediated ferroptosis.

Issue Release: 2024

Analysis of Self-Assembled Micelle Inhibitory RNA (SAMiRNA) Drug Using Ion-Pairing Reversed-Phase Liquid Chromatography Combined with Mass Spectrometry.

Issue Release: 2024

Preparing and Evaluating the Stability of Therapeutically Relevant Oligonucleotide Duplexes.

Issue Release: 2024

Patient-Derived Exosomes as siRNA Carriers in Ovarian Cancer Treatment.

Issue Release: 2024

NLRP4E regulates actin cap formation through SRC and CDC42 during oocyte meiosis.

Issue Release: 2024

Multi-omics integration highlights the role of ubiquitination in endometriosis fibrosis.

Issue Release: 2024

siRNA incorporated in slow-release injectable hydrogel continuously silences DDIT4 and regulates nucleus pulposus cell pyroptosis through the ROS/TXNIP/NLRP3 axis to alleviate intervertebral disc degeneration.

Issue Release: 2024

Targeted siRNA Therapy for Psoriasis: Translating Preclinical Potential into Clinical Treatments.

Issue Release: 2024

Regulating tumor innervation by nanodrugs potentiates cancer immunochemotherapy and relieve chemotherapy-induced neuropathic pain.

Issue Release: 2024

Why is Medication Adherence Important?

Why are Collaborative Care Models Important in Pharma?

How Can Pharmacists Contribute to Transitional Care?

How are ADEs Detected and Reported?

How Can Cellular Stress Be Measured?

What are the Benefits of Collaborative Care Models?

What Should Be Included in Patient Education Materials?

Why Are Clinical Trials Important?

What are Contract Research Organizations (CROs)?

What is Cellular Stress?

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