Lanosterol 14α Demethylase - Pharma

Relevant Publications

New thymol-derived triazole exhibits promising activity against Trichophyton rubrum.

Issue Release: 2024

Synergistic activity of crocin and crocin loaded in niosomes alone and in combination with fluconazole against Candida albicans isolates: In vitro and in silico study.

Issue Release: 2024

Discovery of Novel α,β-Unsaturated Amide Derivatives as Candidate Antifungals to Overcome Fungal Resistance.

Issue Release: 2024

Development of posaconazole nanocrystalline solid dispersion: preparation, characterization and in vivo evaluation.

Issue Release: 2024

Functional Plasticity, Redundancy, and Specificity of Lanosterol 14α-Demethylase in Regulating the Sensitivity to DMIs in .

Issue Release: 2024

Synthesis, Antimicrobial - Cytotoxic Evaluation, and Molecular Docking Studies of Quinolin-2-one Hydrazones Containing Nitrophenyl or Isonicotinoyl/Nicotinoyl Moiety.

Issue Release: 2024

Combined in vitro/in silico approaches, molecular dynamics simulations and safety assessment of the multifunctional properties of thymol and carvacrol: A comparative insight.

Issue Release: 2023

Rhamnopyranoside-Based Fatty Acid Esters as Antimicrobials: Synthesis, Spectral Characterization, PASS, Antimicrobial, and Molecular Docking Studies.

Issue Release: 2023

Aneuploidy Formation in the Filamentous Fungus Aspergillus flavus in Response to Azole Stress.

Issue Release: 2023

Oteseconazole: a long-awaited diversification of the antifungal arsenal to manage recurrent vulvovaginal candidiasis (RVVC).

Issue Release: 2023

The expression pattern, subcellular localization and function of three sterol 14α-demethylases in .

Issue Release: 2023

Synthesis of vanillin derivatives with 1,2,3-triazole fragments and evaluation of their fungicide and fungistatic activities.

Issue Release: 2023

Structural modeling of cytochrome P450 51 from a deep-sea fish points to a novel structural feature in other CYP51s.

Issue Release: 2023

New miconazole-based azoles derived from eugenol show activity against Candida spp. and Cryptococcus gattii by inhibiting the fungal ergosterol biosynthesis.

Issue Release: 2023

Non-target biotransformation enzymes as a target for triazole-zinc mixtures.

Issue Release: 2023

Presence of Aspergillus fumigatus with the TR/L98H Cyp51A mutation and other azole-resistant aspergilli in the air of a zoological park.

Issue Release: 2023

Mechanisms of pathogenicity and the quest for genetic modifiers of kidney disease in branchiootorenal syndrome.

Issue Release: 2023

Purification and structure elucidation of derived antifungal compound with potential anti-Candida property: in silico and in vitro evidence.

Issue Release: 2023

Recent advances in antifungal drug development targeting lanosterol 14α-demethylase (CYP51): A comprehensive review with structural and molecular insights.

Issue Release: 2023

Characterization of the Sterol 24-C-Methyltransferase Genes Reveals a Network of Alternative Sterol Biosynthetic Pathways in .

Issue Release: 2023

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Lanosterol 14α Demethylase - Pharma

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