3rs (replacement, Reduction, Refinement) - Pharma

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Relevant Publications

The partnership between statisticians and the Institutional Animal Care and Use Committee (IACUC).

Issue Release: 2024

Toward an integrated ethical review process: an animal-centered research framework for the refinement of research procedures.

Issue Release: 2024

An Improved Method for Toxicological Profiling of Chemical Substances.

Issue Release: 2024

Exploring Alternatives for Marine Toxicity Testing: Initial Evaluation of Fish Embryo and Mysid Tests.

Issue Release: 2024

OBSERVE: guidelines for the refinement of rodent cancer models.

Issue Release: 2024

Transcriptomic Point of Departure (tPOD) of androstenedione in zebrafish embryos as a potential surrogate for chronic endpoints.

Issue Release: 2024

Use and Reuse of Animal Behavioral, Molecular, and Biochemical Data in Alzheimer\'s Disease Research: Focus on 3Rs and Saving People\'s Tax Dollars.

Issue Release: 2024

Development of an AI-Assisted Embryo Selection System Using Iberian Ribbed Newts for Embryo-Fetal Development Toxicity Testing.

Issue Release: 2024

Conceptual foundations for a clarified meaning of the 3Rs principles in animal experimentation.

Issue Release: 2024

The New Paradigm in Animal Testing - \"3Rs Alternatives\".

Issue Release: 2024

Exploring rabbit as a nonrodent species for general toxicology studies.

Issue Release: 2024

[Prediction of Cardiac Toxicity by Anti-cancer Drugs Using iPSC Cardiomyocytes].

Issue Release: 2024

Protecting Human and Animal Health: The Road from Animal Models to New Approach Methods.

Issue Release: 2024

Development of a canine artificial colonic mucus model for drug diffusion studies.

Issue Release: 2024

In vitro Models for Predicting Bioadhesion Fracture Strength to Ex Vivo Animal Buccal Tissue.

Issue Release: 2024

Naturally sterile Mus spretus hybrids are suitable for the generation of pseudopregnant embryo transfer recipients.

Issue Release: 2024

Big data and its impact on the 3Rs: a home cage monitoring oriented review.

Issue Release: 2024

Noise as an Extrinsic Variable in the Animal Research Facility.

Issue Release: 2024

Development of a Zebrafish Embryo-Based Test System for Thyroid Hormone System Disruption: 3Rs in Ecotoxicological Research.

Issue Release: 2024

Resource and animal use implications of the proposed REACH information requirements for endocrine disruptor assessment.

Issue Release: 2024

Who Can Participate in Clinical Trials?

Who are Pharmacists?

How are New Drugs Discovered?

What are the Challenges in Implementing Collaborative Care Models?

What is an Abbreviated New Drug Application (ANDA)?

What are the Key Challenges?

Why is Patient Education Important?

How Does Pharma Play a Role in Chronic Conditions?

What is Medication Management?

Why is Medication Management Important?

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